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Aims: Biophotonics and Microfluidics research at Tyndall National Institute focuses on the integration of photonics, fabrication and microfluidic technologies within customised lab on a chip devices for specific life science applications.

Available Technologies: In order to achieve these aims extensive simulation of fluidic structures has been carried out to investigate channel properties (shape, dimensions, substrate material) and model fluidic properties (velocity, viscosity, temperature) to assess their impact on fluid flow. Subsequent device development involves rapid proto typing of microfluidic structures in SU-8 and PDMS by photolithography. Reproducible microfluidic interconnections can be realised by customized UV and epoxy bonding processes to minimise dead volume and ensure efficient sample delivery to various on-chip detectors. Hot embossing also provides a rapid and cost effective means to produce different microfluidic chips which can be integrated with various light sources and photo-detector to facilitate in-situ lab on a chip analysis.

Research Interests:

• Design, Modelling and Analysis of Microfluidic Transport with Coventor software
• Electrowetting
• Development and detection of encoded microbeads in a versatile microfluidic platform
• Microchip liquid chromatography
• Synthesis and characterisation of nanoparticles in a microfluidic environment
• Microchip electrophoresis of pharmaceutical analytes
• Chemiluminescent detection of allergens with a nanospad matrix detector