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Leader in Integrated ICT Hardware & Systems

PhD in Biomedical Sensing

SAE- 18 PhD in Biomedical Sensing 

Contract: Full Time/Fixed Term

Summary of project

Biomedical sensing refers to the detection to quantification and analysis of tissue biomarkers by exploiting the various effects of light-tissue interaction. Biophotonic imaging methods as stand-alone techniques are typically highlighting only an aspect of pathological alterations. To improve the diagnostic potential, it has been shown that the combination of different spectroscopic imaging methods (e.g., Optical Coherence Tomography - OCT, SHG, TPEF, CARS, SRS, Raman etc.) into a multimodal approach is very beneficial in providing conceptually novel insights into complex biological media.

In this project, an integrated multimodal and hyperspectral micro-camera system will be engineered to maximize the fluorescence and diffuse reflectance sensing. The sensitivity of micro-camera system will be advanced by means of developing novel imaging methods, device optics engineering, photon migration simulations, data collection and image processing. The project will explore to enhance micro-cameras for specular, fluorescence, diffuse reflectance imaging. A benchtop fluorescence lifetime capability will be explored to advance signal sensitivity and biomarker detection capabilities. The project will involve bench marking the system with existing state of the art point sensing systems. The integrated system will be systematically validated by means of series of tissue mimicking phantoms followed by demonstration on biological tissue. The clinical extension of the project will be evaluated.

The work will be carried out at biophotonics@tyndall group, the student will work in close collaboration with cohort of PhD students, post docs, PIs in biomedical theme.

Key Responsibilities 

  • Carry out innovative research in Microcameras with focus on biomedical sensing.
  • Perform modelling and analysis of photon migration in tissue.
  • Participate on research projects under the direction of supervisors related to microcameras and applications.
  • With guidance, implement the novel solutions in lab, carry out various characterisation and validation of device. 
  • Work on collaborative research projects with industry partners. 
  • Engage in the dissemination of the results of the research, as directed by and with the support of supervisors.
  • Participate in Education and Public Engagement activities, as required.
  • Ensure all activities are compliant with the Tyndall Quality Management system and required Health & Safety standards.
  • Carry out any additional duties as may reasonably be required within the general scope and level of the PhD.

Essential Criteria

  • The ideal applicants will have a 1st Class Honours degree or an MSc in Physics, Engineering or a related discipline.
  • Knowledge of building and handling optics system, programming skills would be advantageous, but is not essential.

An annual student stipend of €18,500 applies for the successful candidate for this position. Yearly University Academic Fees will be paid by the Tyndall National Institute.

Application Instructions

Step 1 - Click here to download and complete the Application form and indicate the Job Reference SAE-18

 Step 2 – Return the completed Application form, together with your CV and motivation letter to

Postgraduate applicants whose first language is not English must provide evidence of English language proficiency ( as per UCC regulations. Certificates should be valid (usually less than 2 years old) and should be uploaded with their application. In special circumstances the panel may consider a prior degree in English (e.g. Master thesis written in English) as evidence of English language proficiency.

Please note that Garda vetting and/or an international police clearance check may form part of the selection process.

The University, at its discretion, may undertake to make an additional appointment(s) from this competition following the conclusion of the process.

Please note that an appointment to posts advertised will be dependent on University approval, together with the terms of the employment control framework for the higher education sector.

At this time, Tyndall National Institute does not require the assistance of recruitment agencies.

Tyndall National Institute at University College, Cork is an Equal Opportunities Employer.