Bioelectronics
Bioelectronics involves the creation of digital healthtech devices and systems, with integrated sensors and systems that can facilitate measurement and monitoring of various parameters, enabling decision support and closed-loop therapeutic systems.
Tyndall’s Bioelectronics research programme is focused on the development and application of electronic devices and systems which interface directly with tissues and/or biofluids in scenarios related to human health.
Research Focus
- Autonomous Biochemical Sensor Systems
- Bioelectronic Medicine
- Smart Delivery Systems.
Bioelectronics Technology Solutions
We investigate and develop new bioelectronics-related solutions encompassing functional materials, sensors and actuators, integrated electronic and photonic components and artificial intelligence and have a demonstrated track record of expertise and technology platforms in the following areas:
Autonomous Biochemical Sensor Systems
- Bioprocessing monitoring
- Microneedle patches for continuous monitoring of interstitial fluid
- Woundcare and wound monitoring
- Implantable sensor systems
- Smart probes/needles.
Bioelectronic Medicine
- Neuralmodulation and electroceuticals
- Implantable leads and electrodes
- Wireless communications and power transfer via tissue and media.
Smart Delivery Systems
- Electromagnetic tracking
- Microneedles/needles
- Catheters and guidewires.
Research making a difference
Discover how researchers at Tyndall are utilising electrochemical sensors to enable early detection of cancer and are developing ways of monitoring the treatment through implantable, wearable and injectable systems.
Recent Publications
- A. Bocchino, S. Teixeira, F. Barry, C. Thatte, A. Ryan, F. Rahman, Y. Hu, S. Iadanza, P. Galvin, S. Kurzhals, E. Melnik, G. C. Mutinati, and C. O’Mahony “Strategies for Passivating Microneedle-based Sensors: Development, Characterization and Comparison”, Sensors and Actuators Reports9, pp. 100328, 2025. https://doi.org/10.1016/j.snr.2025.100328
- C Ferreira, E Lynch, A O’Herlihy, F Barry, LC Nagle, SR Teixeira, P Galvin, Multi-Parametric Electrochemical Sensing Platform: Applications in Animal Welfare, Biosensors 2025, 15(5), 304; https://doi.org/10.3390/bios15050304
- O. P. Singh, I. El-Badawy; S. Sundaram, and C. O’Mahony, “Flexible, Microneedle-based Electrodes: Materials, Fabrication Methods, and Electrophysiological Signal Monitoring – Narrative Review”, Biomedical Microdevices27, 9 (2025). https://doi.org/10.1007/s10544-024-00732-z
- Cristina Cuesta-Marti, Eduardo Ponce-España, Friederike Uhlig, Iris Stoltenborg, Luiza A Wasiewska, Lamiah Kareem, Dara Hedayatpour, Loreto Olavarría-Ramírez, Cristina Rosell-Cardona, Thomaz FS Bastiaanssen, Gabriel SS Tofani, Benjamin Valderrama, Klara Vlckova, Suzanne L Dickson, Aonghus Lavelle, Catherine Stanton, R Paul Ross, John F Cryan, Timothy G Dinan, Gerard Clarke, Siobhain M O’Mahony, Harriët Schellekens, Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice, Nature Communications, 17, Article number: 1653 (2026), https://www.nature.com/articles/s41467-026-68968-2
- M. Srivastava, K. O’Donoghue, A. Siden, A. Jaeger, A. Ferro, D. Crowley, C, van Den Bosch, M. Kennedy, D. O’Hare and P. Cantillon-Murphy,
“3D Position Tracking using On-chip Magnetic Sensing in Image-guided Navigation Bronchoscopy”, IEEE Transactions on Biomedical Circuits and Systems, Apr (2024). -
D Brennan, P Galvin, Evaluation of a machine learning algorithm to classify ultrasonic transducer misalignment and deployment using tinyml, Sensors 24 (2), 560, https://doi.org/10.3390/s24020560
- O. P. Singh, A. Bocchino, T. Guillerm, Y. Hu, F. Stam and C. O’Mahony, “Conductive Fabric Based Flexible Microneedle Electrode for Electrophysiological Monitoring”, Advanced Materials Technologies, pp. 2301606, (2023).
- C. O’Mahony, R. Sebastian, F. Tjulkins, D. Whelan, A. Bocchino, Y. Hu, J. O’Brien, J. Scully, M. Hegarty, A. Blake, I. Slimi, A. Clover, A. Lyness and A.M. Kelleher,
“Hollow silicon microneedles, fabricated using combined wet and dry etching techniques, for transdermal delivery and diagnostics“, International Journal of Pharmaceutics, Volume 637 (2023).
M Marcato, S Tedesco, C O’Mahony, B O’Flynn, P Galvin, Prediction of working outcomes in trainee dogs using the novel Assistance Dog Test Battery (ADTB), Applied Animal Behaviour Science 272, 106212 https://doi.org/10.1016/j.applanim.2024.106212
Recent Projects
- Moore4Medical – Accelerating innovation in emerging medical devices with open technology platforms – https://moore4medical.eu/
- eCAP – eHealth CAPsule for digestive disease diagnostics – https://www.ehealth-cap.eu/
- ELSAH – Electronic smart patch system for wireless monitoring of molecular biomarkers for health and wellbeing – https://www.elsah.researchproject.at/home.php
- ONE Health – Long-term AI research and innovation projects tackling complex, interconnected challenges in human, animal, and environmental health https://www.onehealthproject.co/
- IDEA-FAST – IMI project aiming to provide reliable, objective and sensitive evaluation of activities of daily living and Health – https://idea-fast.eu/
